Buy Metformin Online - Glucophage
Metformin is one of the most effective antidiabetic drugs, used to reduce and maintain blood sugar at a normal level.
The advantage of Metformin over other hypoglycemic drugs is that it does not increase plasma insulin levels and does not cause critically low blood sugar levels.
Metformin provides a clinically significant hypoglycemic effect through:
- Increasing tolerance to glucose
- Slowing down glucose absorption in the digestive tract
- Suppressing the production of glucose by the liver
For daily glycemic control at home, the following can be used:
- Metformin oral solution
- Metformin film-coated tablets
- Extended release Metformin tablets
For hypoglycemic therapy, you should use the dosage form of Metformin that your doctor specified in your prescription.
Diabetic patients who were prescribed long-term antihyperglycaemic therapy, may need to periodically increase or decrease daily doses of this drug. Any changes in the dosage regimen of Metformin should be discussed with your doctor.
Metformin dosing regimen is selected individually, depending on the function of the excretory system, the glycemic balance and the therapeutic response to different drug doses.
- The initial daily dose of Metformin is 850 mg at once; or 1 000 mg, divided into two intakes.
- It is recommended to take no more than 7500 mg of this hypoglycemic drug within 24 hours, divided into three equivalent doses.
- The daily dose of Metformin should be increased gradually, by 500 mg once a week; or by 850 mg once every two weeks.
When a diabetic patient uses high doses of Metformin, he may experience such side effects, as pain or discomfort in the abdomen, upset stomach, severe nausea, headache, asthenia, or vomiting. Reducing the therapeutic dose of Metformin allows you to lower the intensity of adverse reactions.
A very rare adverse reaction that is possible during Metformin use is the lactic acidosis, which causes apathy, myalgia, insomnia, abdominal pain, breathing acceleration, or severe drowsiness. If these symptoms manifest during the medical therapy for diabetes, you should immediately consult a doctor.
The risk of serious adverse reactions of Metformin is very high in diabetic patients, who suffer from metabolic, renal or cardiovascular diseases. Due to this, the drug is contraindicated in:
- congestive cardiac failure
- moderate or severe kidney disease
- metabolic acidosis (ongoing or chronic)
Doctors may adjust Metformin dose from time to time for patients with kidney failure (incl. the elderly with involutional disorders).
If you find out that you are pregnant while using Metformin, you should consult with your doctor about the possibility of its further use. Since the data about the drug influence over the fetus is insufficient, you might be recommended to stop using it.
Metformin is not the drug of choice for breastfeeding women, since it does penetrate into milk. When a woman requires using this medicine while she breastfeeds, she has to make a decision on whether she stops using the drug, or transfers her baby to baby food.
Metformin can be used for both monotherapy and complex treatment of type 2 diabetes. When a patient requires an effective control of his blood sugar level, doctors can prescribe Metformin simultaneously with such antidiabetic medications, like Saxagliptin, Alogliptin, Dapagliflozin or Linagliptin.
Recommendations that help maximize the glycemic control while on Metformin include:
- adhering to a balanced diet
- increasing the daily physical activity
- consuming foods with a low glycemic index